Name | 4'-Demethylpodophyllotoxin |
Synonyms | 4'-demethylpodophyllotoxin 4'-Demethylpodophyllotoxin 5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-isobenzofuro[5,6-f][1,3]benzodioxol-8-one |
CAS | 40505-27-9 |
Molecular Formula | C21H20O8 |
Molar Mass | 400.38 |
Density | 1.446±0.06 g/cm3(Predicted) |
Melting Point | 250-252 °C |
Boling Point | 626.5±55.0 °C(Predicted) |
Appearance | Cryst. |
pKa | 9.94±0.40(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Physical and Chemical Properties | White powder, soluble in methanol, ethanol, DMSO and other organic solvents, comes from Taoer7 Sinopodophyllum hexandrum (Royle) Ying; Rhizome of octagonal lotus Dysosma versipellis (Hance) M. Cheng ex Ying. |
biological activity | 4 '-Demethylpodophyllotoxin is a lignan-like compound contained in Podophyllum hexandrum root and P. peltatum. 4 '-demethlpodophyllotoxin has potential cytotoxicity against a variety of cancer cell lines. |
Use | 4 '-desmethylpodophyllotoxin has antiviral and significant anticancer activity. for content determination/identification/pharmacological experiments, etc |